Our Commitment
Obesity and overweight is estimated to affect more than 2.5 billion adults worldwide, almost 60% of whom are living with at least one co-occurring metabolic, heart, liver, or kidney disease. Despite growing consensus that obesity is a chronic, multifactorial disease, millions of people remain undiagnosed until serious health complications emerge.
At AstraZeneca, our mission is to advance research into the next generation of targeted weight management solutions to deliver not only effective weight loss but also durable long-term weight management solutions for people living with obesity and overweight. This approach has the potential to substantially reduce disease burden and improve health outcomes for patients.

A New Era of Innovation
It’s an exciting time within chronic weight management - an area where the science is quickly evolving and highlighting new pathways and mechanisms that show promise in helping patients to manage their excess weight. In recent years, we’ve seen a new wave of innovation that has improved options for many, but this is coupled with a significant current and growing patient need, with the World Health Organization (WHO) recognising it as one of the most critical public health challenges today and in the future.
AstraZeneca is investing in cutting-edge science to tackle the metabolic, inflammatory, fibrotic, and genetic drivers. Through precision medicine, we aim to develop targeted, personalised therapies that could halt disease progression and prevent cirrhosis or cancer. Our goal is to deliver next-generation therapeutics with unique benefits for people living with this disease of unmet urgent need. Our continued research and innovation focus is on deepening our understanding of the root causes of obesity and overweight, recognising the individual patient needs, preferences, and underlying risk factors to develop next-generation treatments that deliver meaningful full-body health benefits.

Why Join Us?
Backed by AstraZeneca’s leading CVRM portfolio, you’ll champion purpose‑built innovation, novel, complementary treatments designed for durable weight loss with meaningful cardiorenal benefits and turn strong evidence into clear value for healthcare professionals, payers, and health systems. Partnering closely with market access, medical, and marketing, you’ll transform breakthroughs into broad patient access, shape adoption across incretin and non‑incretin approaches, and lead launches that redefine standards. This is a performance‑driven, patient‑focused environment where you can grow your career, build trusted relationships, and deliver real‑world impact for people with obesity, overweight, and type 2 diabetes.
Join us to shape markets, build strategies with real‑world impact, and grow your career where bold ambition meets patient‑centered innovation.

Mina Makar
- Senior Vice President Global Cardiovascular, Renal and Metabolism
At AstraZeneca, our goal is to lead innovation across cardiovascular, renal and metabolic diseases. By integrating cutting-edge science with a deep understanding of how these conditions and obesity or overweight are interconnected, we are committed to delivering transformative solutions that address the full spectrum of patient needs.
Apply Now
- Global Medical Head, Obesity R-237898 Medical Affairs Leaders Boston, Massachusetts
- External Scientific Engagement Director, Obesity R-238678 Medical Information Boston, Massachusetts
- Global Commercial Director Weight Management, CVRM R-238921 Brand Management Boston, Massachusetts
- Medical Director, Kidney Disease, Early Clinical Development CVRM R-234731 Physicians Gothenburg, Sweden
- Senior Medical Director, Kidney Disease, Early Clinical Development CVRM R-234730 Physicians Gaithersburg, Maryland
- Global Commercial Director T2D, CVRM R-238919 Brand Management Boston, Massachusetts
- Clinical Scientist, Early Clinical Development, CVRM R-238344 Clinical Research Scientist Cambridge, United Kingdom
- Clinical Scientist, Early Clinical Development, CVRM R-237144 Clinical Research Scientist Gothenburg, Sweden
- Product Manager GI/GU R-237308 Brand Management Warsaw, Poland
- Brand Manager - CVRM R-238978 Brand Management Petaling Jaya, Malaysia